I have a child between the age of 6 months and 5 years old. Should they get the vaccine? |
Dr. Anne Pham-Huy says, “Yes!” She’s an infectious diseases physician at CHEO and a member of the National Advisory Committee on Immunization (NACI). “If I had a child under 5 years old, there’s no doubt I would make sure they got their vaccine. I’d expect them to catch COVID at some point, but I’d rather not have them go through it without any kind of protection.” |
What do we know about the Moderna vaccine for kids under 6? |
Clinical trial findings show that Moderna’s vaccine, which is 25 micrograms (half the dose given to the age 6 to 11 group), produces an immune response in children under 5 equal to the immune response seen in young adults 18 to 25 years of age who receive the 100-microgram dose primary series. Preliminary efficacy of the vaccine in preventing symptomatic COVID-19 when Omicron is the dominant variant is estimated at 50.6% in children 6 to 23 months of age and 36.8% in children 2 to 5 years of age, starting 14 days after the second dose. However, vaccine efficacy against severe disease is likely much higher.
More information is available in this summary document from the National Advisory Committee on Immunization.
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What is the risk to children under 5 years old from COVID-19? |
With the spread of the Omicron variant, there have been more cases of children under age five in hospital with COVID-19 than earlier in the pandemic. CHEO, for example, has admitting more the 245 kids with COVID-19 since December; more than half of them were under 5.
Neonates are more at risk of hospital admission because they have an immature immune system that has difficulty combatting disease.
Children who have had COVID-19 are at risk of experiencing multisystem inflammatory syndrome (MIS-C), a rare but serious complication that usually requires hospitalization. Children who have an underlying medical condition are at higher risk of severe outcomes from COVID-19. Severe disease and MIS-C can occur in any child, whether they have an underlying condition or not.
Further, all individuals can help protect vulnerable members of their family, including children and youth, by ensuring that they and everyone around them are vaccinated against COVID-19.
Read the full Advisory Committee Statement from NACI for more information.
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Is there a choice of vaccines like adults have? |
For children under 5, the only approved vaccine is Moderna. A vaccine developed by Pfizer is currently under review by Health Canada and a decision is expected in the coming weeks to months. For children who are 5, there are now two approved vaccines, Moderna and Pzifer. |
Should I wait for the Pfizer vaccine? |
If you have decided to vaccinate your child, we encourage you to get the first vaccine that is available. There is no reason to wait. |
Do children aged 6 months to 5 years need one vaccination or two? Is a different vaccine dose used in younger children? |
For the Moderna vaccine (children 6 months to 5 years), there is a two-dose schedule with each dose being 25% of the adult dose. This dose showed similar immune response in the young children as with adolescents and adults. The National Advisory Committee on Immunization (NACI) recommends that the second dose should be given at least eight weeks after the first dose.
Children aged 5 years may receive a two-dose schedule of a smaller Pfizer vaccine dose than the one used in people 12 and older (10 µg instead of 30µg). The National Advisory Committee on Immunization (NACI) recommends that the second dose should be given at least eight weeks after the first dose. Children who turn 12 before their second dose may receive an adult dose.
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How effective is one dose of the vaccine against COVID-19? |
The COVID-19 vaccine is currently a two-dose series for children aged 6 months to 11 years. While one dose provides partial protection in young individuals, it takes both doses to be considered fully vaccinated and optimize the protection provided by vaccination. |
How long do children have to wait between their first and second dose of the COVID-19 vaccine? |
Canada’s National Advisory Committee on Immunization (NACI) recommends children aged 6 months to 11 years receive first and second doses eight weeks apart as this interval is expected to be more beneficial for children in terms of producing longer-lasting immunity and fewer side-effects. While this is NACI’s recommendation, in some cases, the second dose may be administered with a minimum of 21 days between the two doses, as per Health Canada approval. This shorter interval may be considered if informed consent is provided by the child’s caregiver, recognizing the risks and benefits of receiving the second dose earlier than the recommended eight weeks. |
What are the side-effects in children aged 6 months to 5 years? |
The Moderna vaccine is well tolerated in children less than 6 years of age with side-effects generally comparable to the adolescent and adult age groups. These may include feeling tired, chills, muscle aches and pains and a sore or red arm. The majority of children had very mild side-effects or none at all. Typically, these side-effects will go away after a few days and there are no long-term side-effects reported. Side-effects were also comparable to other childhood vaccinations. |
If Moderna has a higher risk of myocarditis youth and young adults, why should I now trust that it’s safe for children under 6? |
In the vaccine trial for children under 6 years of age, there were no reported incidents of myocarditis. |
I’m nursing my baby. Are there any considerations? |
All available COVID-19 vaccines approved in Canada can be used during pregnancy and breastfeeding. Presently, preference is given for the use of mRNA vaccinations during pregnancy as more data on safety and efficacy during pregnancy is available for these vaccines. See the Statement on COVID-19 Vaccination in Pregnancy from the Society of Obstetricians and Gynaecologists of Canada.
Although breastfeeding provides some benefit, providing a COVID-19 vaccine to an infant is the best way to protect them against COVID-19 disease.
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My child is 5. Should I be concerned about the lower Moderna dose not being as effective as the Pfizer dose for kids aged 5 to 11 years? |
There has been no study comparing Pfizer and Moderna products in this age group. The Moderna trial showed that, at the 25-mcg dose, the immune response in children under 6 years was the same as for adults. NACI has recommended offering the Pfizer product in children aged 5 years given the relatively larger experience with this product. |
If my child has had COVID-19, should they get vaccinated? How long should they wait? |
Yes. It is recommended that anyone who has had COVID-19 should still get the vaccine.
The clinical trials included people who previously had COVID-19 and the vaccine was found to be safe for them. Because it is not known how long antibodies against COVID-19 last after infection and it is possible to get the infection again (sometimes more severely), the vaccine is recommended as it can be helpful in boosting a person's existing immunity to COVID-19.
The National Advisory Committee on Immunization (NACI) suggests an 8-week interval between infection and initiation or completion of a COVID-19 primary series (i.e., 8 weeks after symptom onset or positive test if asymptomatic). This interval may be shortened for children considered moderately to severely immunocompromised (e.g., 4 to 8 weeks after symptom onset or positive test if asymptomatic).
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I am behind on my child’s routine vaccinations. Can I get my child’s routine vaccinations at the same time as their COVID-19 vaccination? |
Since the COVID-19 vaccine is new in this age group, The National Advisory Committee on Immunization (NACI) is recommending that other vaccines should not be given at the same time as the COVID-19 vaccine, and to wait 14 days between vaccines. |
I am behind on my child’s routine vaccinations. Should I get the COVID-19 vaccination first and then get up to date? |
This is a personal decision and can be discussed with your primary care provider based on risks. For young children, their primary immunization series are important, however during a COVID-19-related surge in the community, one might prioritize the COVID-19 primary vaccine series. |
Is there a vaccine for infants under six months of age? |
No. A vaccine for this age group would require clinical studies to determine the safety and benefits of vaccination. However, babies can receive protection through immunization of the parent during pregnancy and subsequently through breastfeeding. |
How can I protect my unborn baby from COVID-19? |
If you are pregnant, your vaccination is the best way to protect your baby from COVID-19. Vaccination enables you to pass on immunity to your baby while also protecting yourself.
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Does this immunity offer protection after the baby is born? |
Yes, it is well-recognized in other infectious diseases, such as flu and whooping cough (pertussis), that antibodies resulting from vaccination in a pregnant person provide protection for the first six months of an infant’s life. Multiple studies, including this from the U.S. CDC, have also shown that infants born to those who are vaccinated have more antibodies against COVID-19 and are less likely to be admitted to the hospital with COVID-19. If the pregnant person has not been vaccinated or infected, the baby does not have the protection of antibodies transferred from the parent during the third trimester of pregnancy. |
I cannot decide if vaccinating my child is the right thing to do. Who can I talk to? |
Contact your child’s primary care provider or the SickKids COVID-19 Vaccine Consult Service, a by-appointment phone service for Ontario residents that provides a safe, judgment-free space to have an open conversation about the COVID-19 vaccine with a pediatric registered nurse.
Book an appointment online at www.sickkids.ca/vaccineconsult or by calling 1-888-304-6558.
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